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Xarelto is commonly used as a solution for atrial fibrillation, deep vein thrombosis, pulmonary embolism, and relief after hip or knee replacement. The drug is one of the most frequently prescribed blood thinners in the nation.

Currently, there are more than 20 million regularly refilled Xarelto prescription in the nation. Certain patients have the opportunity to be approved for a $0 co-pay card, though this is not offered to patients enrolled in Medicare Part D or Medicaid.


Patients using Xarelto for atrial fibrillation are at a notably higher risk for getting blood clots in their hearts. In the worst case scenarios, blood clots could potentially travel up to the brain; this can directly cause the onset of a stroke. Xarelto is intended to help lower the chance of a stroke by ideally preventing the initial blood clot that would learn to its onset.


Patients are advised to take Xarelto once or twice a day as prescribed by their primary health care providers. It is meant to be taken alongside food at the same time each day.

If a daily dose of Xarelto is missed, and it is regularly taken twice a day, then the patient should be sure to take Xarelto at the usual time on the next day. Patients make two at the same time to compensate for a missed dosage on the previous day.

In the event that a Xarelto dosage is missed, and a patient regularly takes one dosage per day, then the next dose may be taken as soon as they remember at the regularly scheduled time on the following day.

Patients who are taking this drug after hip or knee replacement surgery are instructed to take Xarelto just one time a day, with or without a meal.


Prospective patients should be advised that because Xarelto is a blood thinner, using it regularly does come with the chance of increased bleeding. If patients happen to be using another drug that increase blood flow, then the risk of bleeding complications might be increased.

Possible side-effects include nosebleeds, bleeding from the gums, heavier menstrual flow, discolored urine, bloody vomit, headaches, wound swelling, and/or an overall higher sensitivity to bruising could potentially be increased.

Patients who regularly take drugs such aspirin or selective serotonin re-uptake inhibitors (SSRIs), then they should consult their primary health care provider before taking any dosages of this drug.

Patients who are scheduled for any types of medical spine injections, or patients who have spine punctures, might be at risk of developing a blood clot that could potentially worsen into the state of total paralysis.

The risk of developing a spinal blood clot can be increased if the spinal medicine is administered with the use of epidural catheter. Other risk factors for spinal blood cots include NSAID use, a history of spinal punctures, or a history of general spinal complications.

Any patients who frequently receive or plan to receive spinal anesthesia should have their primary healthcare provider closely monitor them for any warning signs of spinal/epidural blood clots while taking Xarelto. In there are any sensations of pain, tingling, numbness or muscle weakness while taking it, a doctor should be consulted immediately.

Patients with a history of bleeding problems, kidney complications, or any other pronounced medical issues should make a point to consult their doctor before taking this drug. Women who are pregnant or plan to become pregnant should be advised that it is currently unknown whether or not Xarelto will have an effect on unborn babies or babies who feed from women who are taking Xarelto.

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